Sridharan Rajamani: шукати на сайті Z-Library

Sridharan Rajamani, Christian Studenik, Rosa Lemmens-Gruber, Peter Heistracher

Рік:

2010

Мова:

english

Файл:

PDF, 1006 KB

english, 2010

Cardiotoxic effects of fenfluramine hydrochloride on isolated cardiac preparations and ventricular myocytes of guinea-pigs

Журнал:

Lee L Eckhardt, Sridharan Rajamani, Craig T January

Рік:

2000

Мова:

english

Файл:

PDF, 246 KB

english, 2000

Protein trafficking abnormalities: a new mechanism in drug-induced long QT syndrome

Журнал:

Ryoko Hirakawa, Nesrine El-Bizri, John C. Shryock, Luiz Belardinelli, Sridharan Rajamani

Рік:

2005

Мова:

english

Файл:

PDF, 80 KB

english, 2005

Block of Na+ currents and suppression of action potentials in embryonic rat dorsal root ganglion neurons by ranolazine

Журнал:

Neuropharmacology

Рік:

2012

Мова:

english

Файл:

PDF, 1.18 MB

english, 2012

Ultra-rapid kinetic interactions of ranolazine with Herg K+ current

Sridharan Rajamani, John C. Shryock, Luiz Belardinelli

Журнал:

Journal of Molecular and Cellular Cardiology

Рік:

2007

Мова:

english

Файл:

PDF, 63 KB

english, 2007

Block of Tetrodotoxin-sensitive, Nav1.7, and Tetrodotoxin-resistant, Nav1.8, Na+ Channels by Ranolazine

Rajamani, Sridharan, Shryock, John, Belardinelli, Luiz

Журнал:

El-Bizri, Nesrine, Shryock, John C., George, Alfred L., Belardinelli, Luiz, Rajamani, Sridharan

Рік:

2009

Мова:

english

Файл:

PDF, 56 KB

english, 2009

Use-Dependent Block of Nav1.4 Human Paramyotonia Congenita Mutation By Ranolazine

Журнал:

Journal of Cardiac Failure

Рік:

2010

Мова:

english

Файл:

PDF, 36 KB

english, 2010

New Insights into the Beneficial Electrophysiologic Profile of Ranolazine in Heart Failure: Prevention of Ventricular Fibrillation With Increased Postrepolarization Refractoriness and Without Drug-Induced Proarrhythmia

Gerrit Frommeyer, Sridharan Rajamani, Fabian Grundmann, Jörg Stypmann, Nani Osada, Günter Breithardt, Luiz Belardinelli, Lars Eckardt, Peter Milberg

Журнал:

Рік:

2012

Мова:

english

Файл:

PDF, 1.01 MB

english, 2012

Ranolazine Reduces Central Neuron Excitability by Slowly Interacting with NaV Channels

Hirakawa, Ryoko, Kahlig, Kristopher M., Shan, Mu, Liu, Lynda V., Shryock, John C., Belardinelli, Luiz, Rajamani, Sridharan

Журнал:

Peters, Colin H., Rajamani, Sridharan, Ruben, Peter C.

Рік:

2012

Мова:

english

Файл:

PDF, 41 KB

english, 2012

Ranolazine Effects on NaV1.2 and Modulation by pH

Журнал:

Zygmunt, Andrew C., Nesterenko, Vladislav V., Rajamani, Sridharan, Hu, Dan, Barajas-Martinez, Hector, Belardinelli, Luiz, Antzelevitch, Charles

Рік:

2012

Мова:

english

Файл:

PDF, 55 KB

english, 2012

Mechanism of the Preferential Block of the Atrial Sodium Current by Ranolazine

Журнал:

Рік:

2009

Мова:

english

Файл:

PDF, 43 KB

english, 2009

Dynamic Late Na Current During Cardiac Action Potential Revealed by a Specific and Potent Inhibitor Gs967

Jian, Zhong, Horvath, Balazs, Banyazs, Tamas, Izu, Leighton T., Chen, Yi-Je, Rajamani, Sridharan, Ginsburg, Kenneth, Bossuyt, Julie, Bers, Donald M., Belardinelli, Luiz, Chen-Izu, Ye

Журнал:

Hirakawa, Ryoko, Liu, Lynda V., Shryock, John C., Belardinelli, Luiz, Rajamani, Sridharan

Рік:

2014

Мова:

english

Файл:

PDF, 86 KB

english, 2014

Enhancement of Slow Inactivation of Voltage-Gated Na+ Channels by Ranolazine

Журнал:

Рік:

2011

Мова:

english

Файл:

PDF, 66 KB

english, 2011

Effect of ranolazine on ventricular repolarization in class III antiarrhythmic drug-treated rabbits

Frommeyer, Gerrit, Kaiser, Dennis, Uphaus, Timo, Kaese, Sven, Osada, Nani, Rajamani, Sridharan, Belardinelli, Luiz, Breithardt, Günter, Eckardt, Lars, Milberg, Peter

Журнал:

Rajamani, Sridharan, Kilby, Jennifer, Slind, Jessica, Balijepalli, Ravi C., Anderson, Corey L., Anson, Blake D., Kamp, Timothy J., January, Craig T.

Рік:

2012

Мова:

english

Файл:

PDF, 1.68 MB

english, 2012

N-linked glycosylation is not obligatory for rescue of trafficking-defective LQT2 mutations

Журнал:

El-Bizri, Nesrine, Nguyen, Steven, Liu, Gongxin, Belardinelli, Luiz, Rajamani, Sridharan

Рік:

2005

Мова:

english

Файл:

PDF, 73 KB

english, 2005

Selective Inhibition of Late Na+ Current Reduces Arrhythmic Activity in Spontaneously Hypertensive Rat Myocytes

Журнал:

Makielski, Jonathan C., Belardinelli, Luiz, Rajamani, Sridharan, El-Bizri, Nesrine, Shryock, John C.

Рік:

2014

Мова:

english

Файл:

PDF, 85 KB

english, 2014

Use-dependent block of cardiac late Na+ current by ranolazine

Журнал:

Hirakawa, Ryoko, Belardinelli, Luiz, Rajamani, Sridharan

Рік:

2009

Мова:

english

Файл:

PDF, 1.20 MB

english, 2009

Block of Na+ Currents and Suppression of Action Potentials in Cultured Hippocampal Neurons by Gs-458967

Журнал:

Peters, Colin H., Sokolov, Stanislav, Rajamani, Sridharan, Ruben, Peter C.

Рік:

2014

Мова:

english

Файл:

PDF, 41 KB

english, 2014

Proton Modulation of Ranolazine Effects on Slow Inactivation in Sodium Channels

Журнал:

Kahlig, Kris M., Liu, Lynda, Shryock, John C., Belardinelli, Luiz, Rajamani, Sridharan

Рік:

2013

Мова:

english

Файл:

PDF, 93 KB

english, 2013

Simulated Block of Brain Na+ Channels by Ranolazine Predicts Selective Binding to Inactivated Conformations

Журнал:

Hu, Dan, Barajas-Martínez, Hector, Pfeiffer, Ryan, Dezi, Fabio, Pfeiffer, Jenna, Buch, Tapan, Betzenhauser, Matthew J., Belardinelli, Luiz, Kahlig, Kristopher M., Rajamani, Sridharan, DeAntonio, Harry

Рік:

2012

Мова:

english

Файл:

PDF, 42 KB

english, 2012

Mutations in SCN10A Are Responsible for a Large Fraction of Cases of Brugada Syndrome

Журнал:

Anderson, Lyndsey L., Thompson, Christopher H., Hawkins, Nicole A., Nath, Ravi D., Petersohn, Adam A., Rajamani, Sridharan, Bush, William S., Frankel, Wayne N., Vanoye, Carlos G., Kearney, Jennifer A.

Рік:

2014

Мова:

english

Файл:

PDF, 2.29 MB

english, 2014

Antiepileptic activity of preferential inhibitors of persistent sodium current

Журнал:

Epilepsia

Рік:

2014

Мова:

english

Файл:

PDF, 933 KB

english, 2014

If inhibition in the atrioventricular node by ivabradine causes rate-dependent slowing of conduction and reduces ventricular rate during atrial fibrillation

Verrier, Richard L., Bonatti, Rodolfo, Silva, Ana F.G., Batatinha, Julio A.P., Nearing, Bruce D., Liu, Gongxin, Rajamani, Sridharan, Zeng, Dewan, Belardinelli, Luiz

Журнал:

Belardinelli, Luiz, Giles, Wayne R., Rajamani, Sridharan, Karagueuzian, Hrayr S., Shryock, John C.

Рік:

2014

Мова:

english

Файл:

PDF, 2.24 MB

english, 2014

Cardiac late Na+ current: Proarrhythmic effects, roles in long QT syndromes, and pathological relationship to CaMKII and oxidative stress

Журнал:

Liu, Gong Xin, Remme, Carol Ann, Boukens, Bastiaan J., Belardinelli, Luiz, Rajamani, Sridharan

Рік:

2015

Мова:

english

Файл:

PDF, 899 KB

english, 2015

Overexpression of SCN5A in mouse heart mimics human syndrome of enhanced atrioventricular nodal conduction

Журнал:

The Journal of Physiology

Рік:

2015

Мова:

english

Файл:

PDF, 2.93 MB

english, 2015

In silico assessment of drug safety in human heart applied to late sodium current blockers

Trenor, Beatriz, Gomis-Tena, Julio, Cardona, Karen, Romero, Lucia, Rajamani, Sridharan, Belardinelli, Luiz, Giles, Wayne R, Saiz, Javier

Журнал:

Channels

Рік:

2013

Мова:

english

Файл:

PDF, 3.71 MB

english, 2013

A computational modelling approach combined with cellular electrophysiology data provides insights into the therapeutic benefit of targeting the late Na + current

Yang, Pei-Chi, Song, Yejia, Giles, Wayne R., Horvath, Balazs, Chen-Izu, Ye, Belardinelli, Luiz, Rajamani, Sridharan, Clancy, Colleen E.

Журнал:

Рік:

2015

Мова:

english

Файл:

PDF, 1.53 MB

english, 2015

Selective Inhibition of the Late Sodium Current has No Adverse Effect on Electrophysiological or Contractile Function of the Normal Heart

Fernandes, Sarah, Hoyer, Kirsten, Liu, Gongxin, Wang, Wei-Qun, Dhalla, Arvinder K., Belardinelli, Luiz, Rajamani, Sridharan

Журнал:

Journal of Cardiovascular Pharmacology

Рік:

2014

Мова:

english

Файл:

PDF, 519 KB

english, 2014

SELECTIVE LATE INA INHIBITION BY GS967 EXERTS POTENT SUPPRESSION OF CATECHOLAMINE-INDUCED VENTRICULAR TACHYCARDIA

Bento, Afonso Alves, Bacic, Danilo, Carneiro, Juliana Saran, Nearing, Bruce, Rajamani, Sridharan, Belardinelli, Luiz, Verrier, Richard

Журнал:

Verrier, Richard L., Carneiro, Juliana S., Bento, Afonso Alves, Bacic, Danilo, Nearing, Bruce, Rajamani, Sridharan, Belardinelli, Luiz

Рік:

2015

Мова:

english

Файл:

PDF, 411 KB

english, 2015

THE LATE SODIUM CURRENT INHIBITOR GS967 SUPPRESSES SPONTANEOUS ATRIAL FIBRILLATION IN AN INTACT PORCINE MODEL

Журнал:

Trenor, Beatriz, Cardona, Karen, Saiz, Javier, Rajamani, Sridharan, Belardinelli, Luiz, Giles, Wayne R.

Рік:

2015

Мова:

english

Файл:

PDF, 523 KB

english, 2015

Carbon monoxide effects on human ventricle action potential assessed by mathematical simulations

Журнал:

Frontiers in Physiology

Рік:

2013

Мова:

english

Файл:

PDF, 1.05 MB

english, 2013

Selective Late INa Inhibition by GS-458967 Exerts Parallel Suppression of Catecholamine-Induced Hemodynamically Significant Ventricular Tachycardia and T-Wave Alternans in an Intact Porcine Model

Alves Bento, Afonso S., Bacic, Danilo, Carneiro, Juliana Saran, Nearing, Bruce D., Fuller, Henrique, Justo, Fernanda A., Rajamani, Sridharan, Belardinelli, Luiz, Verrier, Richard L.

Журнал:

VERRIER, RICHARD L., SILVA, ANA F.G., BONATTI, RODOLFO, BATATINHA, JULIO A.P., NEARING, BRUCE D., LIU, GONGXIN, RAJAMANI, SRIDHARAN, ZENG, DEWAN, BELARDINELLI, LUIZ

Рік:

2015

Мова:

english

Файл:

PDF, 896 KB

english, 2015

Combined Actions of Ivabradine and Ranolazine Reduce Ventricular Rate During Atrial Fibrillation

Журнал:

Journal of Cardiovascular Electrophysiology

Рік:

2015

Мова:

english

Файл:

PDF, 665 KB

english, 2015

Ranolazine block of human Na v 1.4 sodium channels and paramyotonia congenita mutants

El-Bizri, Nesrine, Kahlig, Kristopher M., Shyrock, John C., George, Jr., Alfred L., Belardinelli, Luiz, Rajamani, Sridharan

Журнал:

Channels

Рік:

2011

Мова:

english

Файл:

PDF, 1.05 MB

english, 2011

Rapid Kinetic Interactions of Ranolazine With HERG K+ Current

Rajamani, Sridharan, Shryock, John C, Belardinelli, Luiz

Журнал:

Journal of Cardiovascular Pharmacology

Рік:

2008

Мова:

english

Файл:

PDF, 332 KB

english, 2008

Unmasking atrial repolarization to assess alternans, spatiotemporal heterogeneity, and susceptibility to atrial fibrillation

Verrier, Richard L., Fuller, Henrique, Justo, Fernanda, Nearing, Bruce D., Rajamani, Sridharan, Belardinelli, Luiz

Журнал:

Justo, Fernanda, Fuller, Henrique, Nearing, Bruce, Rajamani, Sridharan, Belardinelli, Luiz, Verrier, Richard

Рік:

2016

Мова:

english

Файл:

PDF, 1.47 MB

english, 2016

SELECTIVE INHIBITION OF THE CARDIAC LATE SODIUM CURRENT WITH ELECLAZINE PROTECTS AGAINST ISCHEMIA-INDUCED ATRIAL FIBRILLATION AND VULNERABILITY TO VENTRICULAR ARRHYTHMIAS

Журнал:

Fuller, Henrique, Justo, Fernanda, Nearing, Bruce, Rajamani, Sridharan, Belardinelli, Luiz, Verrier, Richard

Рік:

2016

Мова:

english

Файл:

PDF, 482 KB

english, 2016

THE LATE SODIUM CURRENT INHIBITOR ELECLAZINE SUPPRESSES ATRIAL PREMATURE BEATS AND ATRIAL FIBRILLATION IN AN INTACT PORCINE MODEL

Журнал:

Fuller, Henrique, Justo, Fernanda, Nearing, Bruce D., Kahlig, Kristopher M., Rajamani, Sridharan, Belardinelli, Luiz, Verrier, Richard L.

Рік:

2016

Мова:

english

Файл:

PDF, 486 KB

english, 2016

Eleclazine, a new selective cardiac late sodium current inhibitor, confers concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in an intact porcine model

Журнал:

Poulet, Claire, Rajamani, Sridharan, Ravens, Ursula, Belardinelli, Luiz

Рік:

2016

Мова:

english

Файл:

PDF, 1.74 MB

english, 2016

Effects of Ik,Ach Channel Inhibitor Tertiapin-Q on Right Atrial Preparations from Patients in Sinus Rhythm and Atrial Fibrillation

Журнал:

CARNEIRO, JULIANA SARAN, BENTO, AFONSO S. ALVES, BACIC, DANILO, NEARING, BRUCE D., RAJAMANI, SRIDHARAN, BELARDINELLI, LUIZ, VERRIER, RICHARD L.

Рік:

2015

Мова:

english

Файл:

PDF, 46 KB

english, 2015

The Selective Cardiac Late Sodium Current Inhibitor GS-458967 Suppresses Autonomically Triggered Atrial Fibrillation in an Intact Porcine Model

Журнал:

Journal of Cardiovascular Electrophysiology

Рік:

2015

Мова:

english

Файл:

PDF, 418 KB

english, 2015

Inhibition of the cardiac late sodium current with eleclazine protects against ischemia-induced vulnerability to atrial fibrillation and reduces atrial and ventricular repolarization abnormalities in the absence and presence of concurrent adrenergic stimulation

Justo, Fernanda, Fuller, Henrique, Nearing, Bruce D., Rajamani, Sridharan, Belardinelli, Luiz, Verrier, Richard L.

Журнал:

Рік:

2016

Мова:

english

Файл:

PDF, 1.29 MB

english, 2016

The novel late Na + current inhibitor, GS-6615 ( eleclazine ) and its anti-arrhythmic effects in rabbit isolated heart preparations

Rajamani, Sridharan, Liu, Gongxin, El-Bizri, Nesrine, Guo, Donglin, Li, Cindy, Chen, Xiao-Liang, Kahlig, Kris, Mollova, Nevena, Elzein, Elfatih, Zablocki, Jeff, Belardinelli, Luiz

Журнал:

Yang, Pei-Chi, El-Bizri, Nesrine, Romero, Lucia, Giles, Wayne R., Rajamani, Sridharan, Belardinelli, Luiz, Clancy, Colleen E.

Рік:

2016

Мова:

english

Файл:

PDF, 1.34 MB

english, 2016

A computational model predicts adjunctive pharmacotherapy for cardiac safety via selective inhibition of the late cardiac Na current

Журнал:

Journal of Molecular and Cellular Cardiology

Рік:

2016

Мова:

english

Файл:

PDF, 1.88 MB

english, 2016

Early somatic mosaicism is a rare cause of long-QT syndrome

Priest, James Rush, Gawad, Charles, Kahlig, Kristopher M., Yu, Joseph K., O’Hara, Thomas, Boyle, Patrick M., Rajamani, Sridharan, Clark, Michael J., Garcia, Sarah T. K., Ceresnak, Scott, Harris, Jason

Журнал:

Proceedings of the National Academy of Sciences

Рік:

2016

Мова:

english

Файл:

PDF, 1.22 MB

english, 2016

Eleclazine, an Inhibitor of the Cardiac Late Sodium Current, Is Superior to Flecainide in Suppressing Catecholamine-Induced Ventricular Tachycardia and T-Wave Alternans in an Intact Porcine Model

Bacic, Danilo, Carneiro, Juliana Saran, Bento, Afonso Alves, Nearing, Bruce D., Rajamani, Sridharan, Belardinelli, Luiz, Verrier, Richard L.

Журнал: